In vitro interactions of approved and novel drugs against Paecilomyces spp.

نویسندگان

  • Montserrat Ortoneda
  • Javier Capilla
  • F Javier Pastor
  • Isabel Pujol
  • Clara Yustes
  • Carolina Serena
  • Josep Guarro
چکیده

We have evaluated the in vitro activity of 15 combinations of antifungal drugs (amphotericin B, itraconazole, voriconazole, albaconazole, ravuconazole, terbinafine, and micafungin) against four isolates of Paecilomyces variotii and three of P. lilacinus. The interaction of terbinafine with the four azoles was synergistic for 53% of the combinations, while the interactions of both amphotericin B and micafungin with the rest of antifungal agents were mainly indifferent.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 48 7  شماره 

صفحات  -

تاریخ انتشار 2004